High-throughput Tier 1 ADME, contextualized into human PK for $199/compound
Run a complete Tier 1 ADME panel on every compound at the cost you'd typically pay for a single assay. Then contextualize the results with Inductive's AI, using validated, gold standard PK projection methods to guide discovery towards the best compounds.
Running programs based on piecemeal data misses out on promising compounds
High-quality ADME data has historically been cost-prohibitive to run on every compound early in a drug program. But individual parameters often miss the full picture of a compound's potential in humans. This leads teams to deprioritize promising scaffolds early on that could lead to fewer design cycles and higher-quality DCs.
Five assays on every compound, contextualized with human PK
ADME-One runs microsomal stability, permeability, kinetic solubility, plasma protein binding, and CYP inhibition on every compound submitted.
Automation holds the cost low enough to profile every compound.
Inductive’s PK projection then combines those measurements into projected human PK, using gold standard methods. Drug hunters can understand each compound’s potential and their program’s holistic SAR much earlier to more effectively guide their program.
[how it works]
Five assays, one integrated workflow
[evidence]
Validated and reproducible data across all five Tier 1 assays
See the Tier 1 ADME results showing high quality, reproducible data across kinetic solubility, microsomal stability, MDCK-MDR1 permeability, plasma protein binding and P450 inhibition.
Verapamil human PK projections based on data generated by ADME-One, align closely with measured human PK.
Understand the profile of every compound
